Press Release
Microvisk secures £2.5 million to develop World’s First Medical Diagnostic SmartStrip®
9 September 2010
Microvisk Technologies, the developer of a handheld system to monitor the blood clotting status of patients taking the drug Warfarin, has raised £2.5 million through a rights issue to existing investors. The round was significantly oversubscribed and completed within four weeks.
The round included investment from Oxford Technology Management, Porton Capital, New Hill (Boston, USA), Midven, the Rainbow Seed Fund, Finance Wales and private investors. In January, Microvisk secured £2m from new and existing investors.
A spin-out company from the Science and Technology Facilities Council, Microvisk is developing the world’s first medical diagnostic strip based on a Micro-Electro-Mechanical System (MEMS) that was originally created as a movement system for nano-robots. MEMS technology is used in devices such as the iPhone and Nintendo Wii as well as in car engines.
Microvisk’s ‘SmartStrip®’ uses sensors to work out the clotting speed of blood from a finger prick sample and the results are displayed on a handheld reader. Trials of the prototype device are progressing and Microvisk will use the new capital to finalise product development and start the testing necessary to secure regulatory approval in Europe and the US. The company is on track to launch the SmartStrip® system onto the market in 2011.
Seven million people in the western world use Warfarin and patients must have regular blood tests at their doctor’s surgery or hospital clinic to ensure they receive the correct dose. Warfarin is affected by food and exercise and if the dose is too low there is a risk of blood clots forming which can result in a stroke or heart attack, while too high a dose can lead to a life threatening bleed.
The Microvisk SmartStrip® enables patients to test their blood clotting ability at home, in the same way as diabetics test for glucose. As such, it reflects the increasing trend for healthcare monitoring to be carried out in the home. In 2008 the US and the German healthcare systems announced that they would pay for all at-risk users of Warfarin to test their blood once a week at home, rather than having to go to the doctor or hospital clinic. The Food and Drug Administration (FDA) estimates that over one million new patients per year start taking Warfarin.
To date, only three companies have developed a test system for blood coagulation that can be used in a doctor’s surgery and although certified for home use, market research shows that doctors feel that they are insufficiently robust and too complex for home use. The Microvisk SmartStrip® is unique in the medical diagnostic world as it is a solid state system that is robust and simple to use at home. It also requires far less blood than other systems, which means less pain for the user. The coagulation status (clotting speed) of the patient is measured by tiny multi-layered paddles on the surface of the strip and a memory chip ensures the device is calibrated to provide the highest levels of accuracy.
John Curtis, chief executive officer of Microvisk, said: “We are delighted to have secured the funding we need to take our first SmartStrip® product through the testing phase towards manufacture and launch next year. We believe that we are well-placed to capture a significant share of the doctor’s office and home tests market for Warfarin patients, which we expect to grow with an increasingly older age population. We also intend to develop other medical diagnostic tests that will run on similar test strips.”
Dr Matthew Frohn, director of Oxford Technology Management, said: “Microvisk has successfully transferred an exciting, proven sensor technology into the medical sector to develop SmartStrip®, which is uniquely designed for patient use at home as well as in the doctor’s office. It was no surprise that this oversubscribed round attracted strong investor support and we look forward to following Microvisk’s continuing progress.”
Mark White of the Rainbow Seed Fund said: “The Rainbow Seed Fund has supported Microvisk since its launch as a spin out company in 2004. We congratulate the Microvisk management team on excellent progress with development of the SmartStrip® product and we are pleased to continue to support the company as it gears up for product launch in 2011.”
Dr John Mihell, investment executive at Finance Wales, said: “Microvisk is a great example of a company targeting a growing market with its potentially world-beating innovative. Finance Wales is pleased to have invested in a second round in Microvisk to support the next phase of its growth. We congratulate the company’s management team on excellent progress with development of the SmartStrip® product.”
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Editors Notes
Press enquiries to: Margaret Henry, PR Consultant.
Tel: +44 (0) 1865 811199 Email: m.henry@oxin.co.uk
Photo available on request
The Microvisk SmartStrip® system which enables patients on Warfarin
to carry out blood tests at home.
About Microvisk Technologies
Founded in 2004, Microvisk Ltd is a UK based company developing Micro
Electro Mechanical Sensors for the international medical market.
Initial research was carried out at the Rutherford Appleton Laboratories
facility in Oxfordshire, managed by the Science and Technology Facilities
Council (STFC). Microvisk was spun of STFC and is owned by a mix of private
and venture capital investors.
Many people suffer from coagulation (blood clotting) disorders and the Microvisk technology is designed to enable patients and clinicians to monitor blood clotting ability and assist in the correct dosage of anti-coagulation medication such as Warfarin.
Microvisk’s first product, the SmartStrip®, will be available as a point-of-care and home use test. The device will conduct the internationally recognised Prothrombin Time or INR test by using a drop of the patient’s whole blood taken by a finger prick. The device is simple to use with a large display and buttons, and is sized to be discreet.
Microvisk's technology works using a different approach to the other
devices and tests currently on the market, which use optical analysis
or chemical reactions. Microvisk uses Micro Electro Mechanical Sensors
(MEMS) on a disposable strip which incorporates a small cantilever to
measure viscosity. The devices can test a small volume of whole blood
making the test less intrusive and effectively removing the need for
a laboratory.
In addition, the strip has its own on-board memory to inform the handheld
instrument of all manufacturing variables and under what conditions the
strip has been kept since the day of its manufacture.
The Prothrombin Time or INR test works by introducing tissue factor to begin the clotting cascade which is the same series of reactions that occur when a blood vessel is ruptured. The clot changes the blood from a free flowing solution to a gel-like substance and it is this change that the sensors monitor and detect.
For more information: www.microvisk.com